Pharmacology of U-47700
U-47700-Pink is a novel synthetic opioid agonist with selective action at the mu-opioid receptor.
- The chemical designation is 3,4-dichloro-N-[2-dimethylamino) cyclohenyl]-N-methylbenzamide.
- It was originally developed by chemists at Upjohn Pharmaceuticals in the 1970’s as a potent pain reliever for use in surgery, cancer, or painful injuries.
- Although it was never commercially made available, the patent and chemical details remained available.
- U-47700 has a similar chemical profile as morphine and other mu-opioid receptor agonists; however, it has been reported by the National Institute of Drug Abuse (NIDA) that Pink is “far more potent than morphine” — possibly seven to eight times more potent.
- The strength of the product can never be assured, and may be much stronger, as it is a designer drug made in illegal labs.
- Animal studies have shown that the analgesic activity of U-47700-Pink was reduced by naltrexone, an opioid receptor antagonist.