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Pharmacology of U-47700

U-47700-Pink is a novel synthetic opioid agonist with selective action at the mu-opioid receptor.
  • The chemical designation is 3,4-dichloro-N-[2-dimethylamino) cyclohenyl]-N-methylbenzamide.
  • It was originally developed by chemists at Upjohn Pharmaceuticals in the 1970’s as a potent pain reliever for use in surgery, cancer, or painful injuries.
  • Although it was never commercially made available, the patent and chemical details remained available.
  • U-47700 has a similar chemical profile as morphine and other mu-opioid receptor agonists; however, it has been reported by the National Institute of Drug Abuse (NIDA) that Pink is “far more potent than morphine” — possibly seven to eight times more potent.
  • The strength of the product can never be assured, and may be much stronger, as it is a designer drug made in illegal labs.
  • Animal studies have shown that the analgesic activity of U-47700-Pink was reduced by naltrexone, an opioid receptor antagonist.