5-Methylethylone (5-methyl-βk-MDEA, 5ME) is an empathogen, stimulant and psychedelic drug of the amphetamine, phenethylamine, and cathinone chemical classes.

5-methylethylone

It is structurally related to ethylone, a novel designer drug. Relatively little data exists about the pharmacological properties, metabolism, and toxicity of 5-methylethylone, though it has been sold as a designer drug.

5-methyl-ethylone med for sale Drug discrimination studies showed that 5-methyl-MDA substitutes for MDA, MMAI, and LSD, but not amphetamine, suggesting that it produces a mix of entactogen and hallucinogenic effects without any stimulant effects.^{[citation needed]}

5-Methyl-MDA acts as a selective serotonin releasing agent (SSRA) with IC₅₀ values of 107nM, 11,600nM, and 1,494nM for serotonin, dopamine, and norepinephrine efflux.^[1] It is over 5 times more potent than MDA in vitro assays, with a suitable active dose possibly in vivo being around 15–25 mg.^[1] Subsequent testing in vivo, however, has found that it is not as potent as once thought and is active at at least 100 mg. 2-Methyl-MDA is also much more potent than MDA, but is not quite as potent as 5-methyl-MDA.^[1] 6-methyl-MDMA (also known as Madam-6) is mostly inactive, likely due to steric hindrance.

Recent research has used data on 2-methyl-MDA and 5-methyl-MDA to help guide computer modeling of the serotonin transporter complex.

Substance

Unspecified amount of Pentylone has been identified in this pill

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Safer use

• Similar-looking pills may still contain completely different substances and/or strengths
• Use drug testing services if possible
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5-METHYLETHYLONE

• Molecular FormulaC₁₃H₁₇NO₃
• Average mass235.279 Da
• Monoisotopic mass235.120850 Da
• ChemSpider ID52084944

This product is also very good for research.