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ADB-BUTINACA is a potent agonist of the CB1 and CB2 receptors and is also a potent indole-based cannabinoid. This research chemical is structurally similar to other popular synthetic cannabinoids such as MDMB-BUTINACA. Anecdotal reports have recorded that participants had exhibited effects of euphoria, relaxation and mood enhancement. We offer adbb (adb-butinaca) for sale online
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ADB-FUBINACA is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.
The (S)-enantiomer of ADB-FUBINACA is described in a 2009 Pfizer patent[3] and has been reported to be a potent agonist of the CB1 receptor and the CB2 receptor with EC50 values of 1.2 nM and 3.5 nM, respectively.[3][4] ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group.
Side effects
One death through coronary arterial thrombosis has been linked to ADB-FUBINACA intoxication.
At least an additional 8 deaths in Hungary in 2015 are linked to the usage of this material, all deaths were youngsters below 21.
Metabolism
Twenty-three ADB-FUBINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation.
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