EG 018 isĀ an analog of JWH 018 that has a benzene ring attached to the aminoalkylindole group, positioned adjacent to the naphthoyl group. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Buy EG-018 Online
Buy EG-018 Online sold online at richchemstore.com has a full IUPAC name of naphthalen-1-yl(9-pentyl-9H-carbazol-3-yl)methanone which belongs to a class of synthetic cannabinoids research chemicals. EG-018 might be a potent cannabinoid agonist at the CB1 and CB2 receptors.
EG-018 is a carbazole-based synthetic cannabinoid that has been sold online as a designer drug.It acts as a partial agonist of the CB1 and CB2 receptor, with reasonably high binding affinity, but low efficacy in terms of inducing a signaling response.
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Technical Information
- DMF: 20 mg/ml
- DMSO: 0.2 mg/ml
Shipping & Storage Information
Metabolism of the new synthetic cannabinoid EGā018 inīhuman hepatocytes by highāresolution mass spectrometry.
A novel SC, EG-018 (naphthalen-1-yl(9-pentyl-9H-car-bazol-3-yl)methanone) was first detected in the United Kingdom in a sampling campaign between July 2013 and January 2015 .
EG-018 was also detected in the Japa-nese regular illegal drug survey and in the state of Ohio in 2014. EG-018 is an analog of scheduled SC JWH-018 and THJ-018 , possessing a similar structural skeleton, a naphthalene and pentyl chain connected via a middle core substructure. In JWH-018, the middle core is an indole, in THJ-018 an indazole, and in EG-018 a carbazole .
EG-018 was the ļ¬rst identiļ¬ed SC with a mid-dle core substructure of three aromatic rings. The binding aļ¬nity of JWH-018 to CB1 is high, while that of EG-018 is unknown. Identifying a new SC intake and its associated adverse eļ¬ects requires elucidation of novel metabolites.
However, all previously investigated SCs were extensively metabolized and excreted primarily in urine, with rare detection of the parent SCs.
