WHAT IS JWH-073 ?
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the
naphthoylindole family that acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors.
It is somewhat selective for the CB1 subtype, with affinity at this subtype
approximately 5x the affinity at CB2.The abbreviation JWH stands for John W. Huffman, one of the inventors of the compound.
On 20 April 2009, JWH-073 was claimed by researchers at the University of
Freiburg to have been found in a “fertiliser” product called “Forest Humus”, along with another synthetic cannabinoid (C8)-CP 47,497.
These claims were confirmed in July 2009 when tests of Spice product, seized
after the legal ban on JWH-018 had gone into effect in Germany, were shown to
contain the unregulated compound JWH-073 instead.
The analgesic effects of cannabinoid ligands, mediated by CB1 receptors are well
established in treatment of neuropathic pain, as well as cancer pain and arthritis.
These compounds work by mimicking the body’s naturally-produced endocannabinoid hormones such as 2-arachidonoylglycerol and anandamide, which are biologically active and can exacerbate or inhibit nerve signaling.
As the cause is poorly understood in chronic pain states, more research and development must be done before we can realize the therapeutic potential of this class of biologic compounds
JWH-073 (Spice Cannabinoid)
100 ug/mL in Acetonitrile |
Certified Reference Material
A synthetic cannabinoid found in several versions of the herbal mixture “Spice,” JWH-073 is considerably more potent than natural THC from cannabis and has an extended duration of action. Illicit use centers on its psychoactive effects which mimic those of Δ9-THC.
Formulation(Request formulation change)
A crystalline solid
Shipping & Storage Information
Room Temperature in continental US; may vary elsewhere
≥ 1 year