Methylone (also known as “3,4-methylenedioxy-N-methylcathinone”, “MDMC”, “βk-MDMA” and by the slang term “M1”) is an empathogen and stimulant psychoactive drug.
It is a member of the substituted amphetamine, substituted cathinone and substituted methylenedioxyphenethylamine classes.
Methylone MED
Methylone is the substituted cathinone analog of MDMA and the 3,4-methylenedioxy analog of methcathinone.
The only structural difference of methylone with respect to MDMA is the substitution of 2 hydrogen atoms by 1 oxygen atom in the β position of the phenethylamine core, forming a ketone group.
Methylone was first synthesized by the chemists Peyton Jacob III and Alexander Shulgin in 1996 for potential use as an antidepressant.
Methylone has been sold for recreational use, taking advantage of the absence of legal prohibition of this compound in many countries
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Methylone (BK-MDMA) Crystals is widely known as a stimulant. This drug causes hallucinogenic effects. In scientific research, this drug is used as a chemical. Be cautious if you are using this drug because it has a very short existence according to the research reports.
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This is a powerful drug and has antidepressant action, pleasant and positive effects. A feeling of calmness can be felt after taking this drug.
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Methylone functions as a serotonin, norepinephrine and dopamine combination reuptake inhibitor / releasing agent. It is roughly 3 times lower in contrast with MDMA to the transporter of serotonin and its affinity is comparable to the transporters of norepinephrine and dopamine.
The vesicular monoamine transport affinity of 2 methylone (VMAT2) is roughly 13x lower than the MDMA affinity.
These pharmacological variations with respect to MDMA are the result of the fact that methylone, as opposed to serotonergic, is dose-less potent and has more regulated catecholaminergic effects and has greater tolerance than an amphetamine-like release agent, and that methylone has a relative robust release capabilities, probably because of its phosphorylated m capabilities.
